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Some research suggests GLP-1 agonists can: 3 Lower cholesterol Decrease the risk of heart disease and kidney disease Lower blood pressure Side effects of GLP-1 agonists When asking your doctor if this type of medication is right for you, remember to consider that it may cause common side effects, including: 3 Diarrhea Headache Nausea Low blood sugar, especially if taking certain medications Vomiting GLP-1s aren't recommended for people with the following medical history: 2 Currently breastfeeding Kidney disease Medullary thyroid cancer Multiple endocrine neoplasia Pancreatitis, inflammation of the pancreas Pregnant or actively trying to get pregnant Types of GLP-1 agonists GLP-1s are FDA-approved to treat type 2 diabetes, weight loss (in certain populations) or both