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Moreover, the complexity of the pathophysiology and genetic diversity result in a significant proportion of patients not responding to the current targeted therapies

GHK was also shown to combat copper-dependent oxidation of low-density lipoproteins, while various other common antioxidants, such as superoxide dismutase, only provided protection against oxidation up to 20%

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One of the most promising interventions is dietary restriction (DR) of either calories in general or specific macronutrients, as it consistently has been shown to prolong life- and healthspan in a broad range of model organisms and possibly humans, too, when compared with unrestricted food intake