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If you're in your 60s and are more concerned about cardiovascular disease and colorectal cancer than bleeding, you might also want to consider taking aspirin, although the risk of bleeding increases with age, USPSTF said

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PPAR controls the transcription of fibroblast growth factor 21 (FGF21), which is preferentially expressed in the liver and stimulates -oxidation of fatty acids to generate ketones [124,125,126]