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Recent reviews have highlighted potential immunomodulatory effects across diverse autoimmune contexts, suggesting that the observed anti-inflammatory properties may extend beyond metabolic improvement (77)

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The interaction between immune components and the gut microbiota is pivotal in the function of the gut-brain-kidney axis, influencing the occurrence and development of other diseases such as inflammatory bowel diseases (IBD), vascular inflammation and cardiovascular diseases, tumors, obesity and metabolic syndrome, nervous system diseases, infectious diseases, and hepatic fibrosis (Wiredu Ocansey et al., 2023)