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In the hippocampus, TRPV4 activates apoptosis through the silencing of the PI3K/Akt pathway (related to oxidative stress [161] ) and by promoting p38/MAPK activation [162]

L.NajasS.BarallobreM

doi: 10.1016/j.ijbiomac.2020.02.319 122 ZhouK.YuL

And so I basically try to focus my efforts on, sort of, converging those two worlds but acknowledging that we're never going to know the answer for certain and we're going to have to use our best judgment around those things and hope that in time certain other things do become available