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Report suspected adverse reactions to B12 supplements via the MHRA Yellow Card Scheme

Other reasons include: bariatric surgery or bowel resection, age, those with GI diseases such as Crohns and Celiac, people taking Metformin to control their blood sugar and thos taking proton pump inhibitors (Prevacid, Prilosec, etc) for chronic heartburn

Elevates NAD+ and S-adenosylmethionine (SAM) levels, shifting metabolic flux toward energy expenditure and away from fat storage 1-4

Vitamin B12 injection : For maximum bioavailability, especially in cases of severe deficiency or malabsorption, intramuscular injections of vitamin B12 offer direct absorption and are often prescribed to rapidly restore adequate levels