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The only difference is the **nominal volume** and what it implies: faster diluent turnover, a limited number of septum punctures, almost no prolonged environmental exposure once opened

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This can be problematic for patients with diabetes because vitamin B-12 is an essential nutrient needed for energy production and is required for the normal functioning of the nervous system

For most people, B12 can be taken at any time of day without affecting sleep, though morning dosing is often recommended for consistency and to address any individual sensitivity