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Also, the drug needs to be taken on an empty stomach immediately on waking, with no more than 120 mL of water

Prompt parenteral administration of vitamin B12 prevents progression of neurologic damage

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As the However, while risks of severe toxicity are low, some side effects are still possible, such as: temporary symptoms, such as itching, swelling, or diarrhea allergic reaction damage from the injection hypokalemia, or low potassium levels infection negative interactions with certain medications, such as: metformin (Fortamet, Glucophage, Riomet) medications to reduce gastric acid, such as proton pump inhibitors or H2 receptor antagonists Always talk with a doctor before using vitamin B12 supplements