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The parameters were assessed by immunohistochemistry and fluorescence light microscopy in nine female participants aged 4468 years

ACS Chem Neurosci 16:818825 Dickson SL, Shirazi RH, Hansson C et al (2012) The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: a new role for mesolimbic GLP-1 receptors

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Each has a different mechanism, a different depth (epidermal, dermal or mixed), a different trigger and a fundamentally different treatment requirement