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Iron (Fe)-redox dysregulation (FeRD) During SARS-CoV-2 infection, free iron released into the circulation induces inflammation of alveolar macrophages and causes oxidative damage to the lungs 144

[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Richie J.P., Nichenametla S., Neidig W., Calcagnotto A., Haley J.S., Schell T.D., Muscat J.E

Combination therapy was associated with a lower risk of primary composite outcomes of all-cause hospitalization, all-cause mortality, major adverse cardiovascular events (MACE), major adverse kidney events (MAKE), and major adverse liver outcomes (MALO) (hazard ratio [HR], 0.87

Thus, it cannot be excluded that in some IBD patients disruption of GI tract homeostasis may be observed leading to development or exacerbation of IBD