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Microbiota-gut-brain axis The knowledge of the existence of a continuous bidirectional communication between the gut and the brain was initially postulated by Hippocrates, Plato and Aristotle [47]

In patients with cirrhosis, the main risk factors for developing overt HE include MHE, sarcopenia, hyponatremia, epilepsy, type 2 diabetes, elevated creatinine, elevated bilirubin, and hypoalbuminemia.1 Because overt HE is a manifestation of decompensated liver failure, it has a negative impact on survival

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She explains how small increases in daily steps can reduce cardiovascular mortality risk and improve mental health, sharing data on how different step counts correlate with health outcomes