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Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

What evidence exists for CJC-1295 in humans

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Furthermore, potential predictors of affective switching with antidepressants may include bipolar I disorder (versus bipolar II), mixed features during depression, tricyclics and partly dual-action inhibitors versus modern antidepressants [26], rapid cycling and possibly a history of drug abuse, especially stimulant abuse [27]