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Peripheral-nerve transection and crush models Here a rodent sciatic (or facial) nerve is cut or crushed, then repair is tracked with the sciatic functional index (a walking-track measurement of toe spread), electromyography, and histomorphometry counting the number, diameter, and myelination of regenerating axons

Cons: Effectiveness depends on dietary intake

Mazdutide Developed by Innovent Biologics in partnership with Eli Lilly, mazdutide is another GLP-1/glucagon dual agonist currently in advanced clinical trials, primarily in China

Similarly, small-scale or non-generalizable animal experiments were excluded if they failed to provide substantial mechanistic insights