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Evolution in an Arabidopsis interactome map

GLP-2 [333] exerts both weak agonism and antagonism at the rodent and human GLP-2 receptors in vitro (82, 83) and in rodents in vivo (82)

10 Multiple, overlapping effects This illustration summarizes some of the ways GLP-1 drugs work across different body systems

This medication works by mimicking the naturally occurring GLP-1 hormone, which enhances insulin secretion in response to meals, suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways