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The peptide is an NNMT (Nicotinamide N-methyltransferase) inhibitor

No Observed Effects On: Blood glucose or insulin sensitivity (no diabetogenic effects) IGF-1 levels (remained within normal ranges) Blood pressure or cardiovascular parameters Thyroid function Liver or kidney function markers Important: The absence of growth hormone-related side effects distinguishes AOD-9604 from full-length GH, which can cause fluid retention, joint pain, carpal tunnel syndrome, and insulin resistance

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The FDA panel has deferred the approval of the drug, pending the conduction of a long-term study demonstrating cardiovascular safety [243] (Table 3 )