A few postpone to accumulate additional evidence or to attempt more conservative interventions initially, such as aspirin, heparin, or lifestyle modifications
However, serum levels may be maintained at normal or borderline levels at the expense of tissue concentrations
In certain embodiments, any controlled release otic formulation or composition described herein increases the exposure of a therapeutic agent and increases the Area Under the Curve (AUC) in otic fluids (e.g., endolymph and/or perilymph) by about 30%, about 40%, about 50%, about 60%, about 70%, about 80%, or about 90% compared to a formulation or composition that is not a controlled release otic formulation or composition
Competitive Advantages for Formulators Clinical differentiation sets LiposoMax Glutathione apart from commodity options