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A : Some ingredients may support natural GLP-1 activity in the body, but the increase is likely small and not comparable to pharmaceutical GLP-1 treatments

Activation of YAP can induce the expression of SLC7A11, thereby enhancing cystine uptake by System XC-, increasing GSH level, thereby increasing GPX4 synthesis, thus reducing ROS level and inhibiting ferroptosis [16, 17]

In patient 3, the normalization of plasma L-carnitine levels was accompanied by improvement of muscle weakness and fatigability, while the degree of -BB accumulation in the plasma remained unchanged upon L-carnitine supplementation

Supplementary Materials Supplementary material related to this article can be found, in the online version