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In preclinical work, BPC-157 has been evaluated in cell-based and animal models, in which investigators examine tissue integrity, barrier function, and responses to experimentally induced stress or injury under controlled conditions

This investigation suggested that GHR has no effect on mitochondrial biogenesis, at least in vitro

After the cells reached ~ 80% confluence under normal culture conditions, the medium was changed to glucose-free DMEM (Gibco) and the dish was placed in an anaerobic chamber (5% CO2, 95% N2) to induce OGD-related cell injury

The committees first vote, on BPC-157, came out in favor of widening access to the peptide