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242244 By potentially mitigating the detrimental effects of oxidative stress, inflammation, and cellular senescence, GLP-1 RAs can contribute to preserving both the functionality and number of stem cells, thus fostering a healthier cellular environment that supports regenerative processes

Key evidence includes: Gastric emptying studies (also called gastric scintigraphy) showing delayed stomach emptying, which is the gold standard test for diagnosing gastroparesis Medical records documenting your GLP-1 prescription, dosage, duration of use, and the timeline of when symptoms began Emergency room records if you sought treatment for severe nausea, vomiting, dehydration, or intestinal blockage Hospitalization records, if you required inpatient treatment for GI complications Diagnostic imaging, such as upper GI series, CT scans, or MRIs, showing intestinal problems Endoscopy or colonoscopy results, if performed to evaluate your symptoms Pharmacy records showing when you filled prescriptions and how long you used the medication Documentation of treatments, including medications for nausea, dietary changes, or surgical interventions If you experienced severe symptoms consistent with gastroparesis but havent undergone gastric emptying studies, talk to your healthcare provider about appropriate testing

TNSALP gene mutations and epilepsy The TNSALP gene, located on chromosome 1p36.12, encodes a tissue non-specific alkaline phosphatase enzyme, which is widely distributed in the liver, bones, kidneys, and developing teeth