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Association of RAGE gene polymorphisms with type 2 diabetes mellitus, diabetic retinopathy and diabetic nephropathy

Others have alluded to the potential protective effect in AMD, but were among the first to show it in a large database study, says lead author Kevin Allan, MD, PhD, a resident at the Cole Eye Institute

The absence of safety data in these populations means that use should be avoided or approached with extreme caution and specialized medical supervision