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The liver is both the primary site of glutathione synthesis and the organ most dependent on it GSH is essential for phase II conjugation reactions that neutralise toxins, drug metabolites, and alcohol breakdown products (acetaldehyde)

Additionally, its role in diabetes and its complications, such as diabetic nephropathy, retinopathy, cardiomyopathy, and microangiopathy, has been intensively studied [23]

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(PubMed) Gerstenberger JP, Bauer SR, Van Blarigan EL, et al