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Shen P, Yue Y, Park Y (2018) A living model for obesity and aging research: Caenorhabditis elegans

Muscle Nerve 71 (2), 171182

Microbiota-induced obesity requires farnesoid X receptor

However, when the body is in conditions such as IR, calorie restriction, inflammation, or eating a high-fat diet, lipogenesis is hindered, causing a higher rate of fat deposition in adipose tissue that can lead to obesity