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This mirrors the clinical trial protocols and significantly reduces side effects

Sex differences in densities of dopaminergic fibers and GABAergic neurons in the prenatal rat striatum

Cardiovascular effects beyond cardiac hypertrophy are poorly characterized for IGF-1 DES specifically, though IGF-1 influences cardiovascular physiology through effects on vascular smooth muscle, endothelial function, blood pressure regulation, and cardiac contractility - chronic perturbation of these processes carries unknown risks