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Applications & Features Model Delivery & Logistics Resources Validation Data Applications of the genOhGLP-1R mouse model Broad range of applications in the fields of metabolism, autoimmunity and neuroscience : Assess the efficacy of GLP-1R targeting compounds, such as in the context of treating type 2 diabetes and obesity Investigate the mode of action (MoA) of various compounds and understand their therapeutic potential Features Physiological regulation and expression of the humanized GLP-1R Fully functional hGLP-1R Lack of expression of the murine target gene Model is available in a C57BL/6N background Fully functional mouse immune system Clients Customize this model Tailor this model to meet your research needs : Assess the efficacy and safety of therapeutics with multiple humanized targets Simultaneously evaluate efficacy, safety, and PK in a single model Assess the impact of the human Fc-domain of an antibody while assessing its efficacy and safety Increase tolerance to human IgG1 and more to fit your program Model Delivery & Care Read our FAQ on delivery & care here Orders are made directly with genOway

Note any side effects and their severity to spot trends and inform dose decisions

That leaves dinner as the primary opportunity to hit protein targets that prevent muscle loss

TRIUMPH-1, -2 and -3 have reported