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These combined effects may exacerbate osteoporosis and increase the risk of fractures

Cederbaum SD, Koo-McCoy S, Tein I, Hsu BY, Ganguly A, Vilain E, Dipple K, Cvitanovic-Sojat L, Stanley C: Carnitine membrane transporter deficiency: a long-term follow up and OCTN2 mutation in the first documented case of primary carnitine deficiency

(29), who demonstrated the presence of two transcripts of genes encoding AANAT and two encoding ASMT in the eyeball at noon and midnight in sticklebacks

6.3 Cardiovascular diseases Cardiovascular diseases (CVDs) are also characterized by insulin resistance, a pro-oxidative and pro-inflammatory state, as well as a dysregulation of the expression of various factors responsible for the homeostasis of redox and inflammatory environment [62]