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The authors justified this result by pointing out the greater regenerative capacity of the redox system in children compared to adults
Mechanistically, silencing CBS impairs H 2 S production, significantly reduces cellular GSH levels, increases ROS production, activates the tumor suppressor p53 and inhibits NF-B activation
Mol Cell Endocrinol 487:4553 Jelinic M et al (2019) From pregnancy to cardiovascular disease: lessons from relaxin-deficient animals to understand relaxin actions in the vascular system
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