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Furthermore, the depletion of arginine restrains Oxphos in the mitochondria, after epigenetic changes (i.e., reduced histone acetylation due to a restricted pool of acetyl-CoA) in tumor cells (breast cancer), impairing tumor development

van der Merwe M, Bloomer RJ

25 found that inhibiting ferroptosis by inhibiting glutamine metabolism could be used to treat tissue damage triggered by I/R in the isolated hearts of wild-type mice

MRI findings The classic finding is T2/FLAIR hyperintensity with diffusion restriction involving the insular gyri and cingulate gyri (with relative sparing of the occipital lobes and perirolandic region