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Results: Effect size for desire: 0.49 to 0.61 Effect size for distress reduction: 0.60 to 0.62 25% of treated patients versus 17% placebo achieved clinically meaningful desire increase 35% versus 31% achieved clinically meaningful distress reduction A 52-week open-label extension confirmed sustained efficacy and safety (PMC6819021, PMC6819023)

Collectively, these trajectory analyses revealed that Lserine fundamentally reprogrammed the metabolic state of IL7R low naive CD4 T cells, and CD4 T cells were moving from a developmental bottleneck toward a functionally competent state, with potential implications for overall immune balance in patients with ASD

Glutathione is naturally produced in the body, but its production can be reduced by environmental and dietary factors