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Lastly, the sample size, while adequately powered for a composite endpoint design [57], can be improved in subsequent studies based on the data from the current one

Before each injection, examine the intended area for firmness, discoloration, or swelling

Communication delays from the medical team

Anyone who suspects they are experiencing a side effect from any medicine or unlicensed compound should report it to the MHRA via the Yellow Card scheme at and contact their GP promptly