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It does not eliminate the need for behavioral changes

14 A so-called therapeutic misadventure phenomenon, as coined by Zimmerman et al ., is becoming increasingly acknowledged, as some patients have presented with acute liver failure despite consumption of safe doses of APAP

However, benefits were still observed across the BMI spectrum, and the effects were generally consistent across multiple subgroups, including those with mildly reduced versus preserved ejection fraction, and those receiving versus not receiving other heart failure medications like mineralocorticoid receptor antagonists and SGLT2 inhibitors at baseline

In vitro reconstitution reveals a key role of human mitochondrial EXOG in RNA primer processing [J]