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This observation was supported by TUNEL staining, which demonstrated a more extensive area of apoptosis in the BNCT H and BNCT L/Dox@vesicles groups than in the control group, with the BNCT L group also showing apoptosis

HIF-1alpha drives resistance to ferroptosis in solid tumors by promoting lactate production and activating SLC1A1

For instance, qPCR analysis of cardiomyocytes from patients with atrial fibrillation revealed an upregulation of E2D2, suggesting a role for this enzyme in the pathogenesis of arrhythmias