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Naidu AK, Karl RC, Naidu KA, Coppola D: The antiproliferative and pro-apoptotic effect of Ascorbyl Stearate in Human pancreatic cancer cells : Association with decreased expression of insulin-like growth factor receptor-1

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Unlike GLP-1 agonists such as semaglutide or tirzepatide, which work primarily through appetite suppression, AOD-9604 directly enhances fat metabolism at the cellular level through beta-3 adrenergic receptor modulation

The FDA warning applies only to medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2), which are different from common thyroid cancers