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ATF6, Activating Transcription Factor 6

This varies by individual: Contrave may be more tolerable for: Patients who dont tolerate GI effects well, who dont have seizure risk or significant cardiovascular concerns, and who prefer oral medication

DIO mice were randomized to treatment according to body weight (n = 15 per group) and dosed subcutaneously (5 ml/kg) for a total of 28 days with vehicle (QD), liraglutide (0.2 mg/kg, BID) or GUB09-145 (0.04 mg/kg, BID)