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In the pivotal STEP 1 clinical trial, participants who received weekly semaglutide injections lost an average of 14.9% of their body weight over 68 weeks , compared with 2.4% in the placebo group (study in the New England Journal of Medicine )

This peptide is not approved for diagnostic, therapeutic, or medical applications

Peripheral vs Central Action AOD-9604 functions exclusively through peripheral mechanisms in adipose tissue rather than through central nervous system pathways that regulate appetite

Additionally, this compound is associated with supporting lean body composition by reducing fat accumulation while maintaining muscle mass