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DOI: 10.1517/17425250903427980 56

Estimates from a meta-analysis suggest that the global prevalence of nonalcoholic fatty liver disease (NAFLD) is 30.1%, with a significant increase from 25.3% (19902006) to 38.2% (20162019) over the last three decades

N6F11 selectively induces ferroptosis in cancer cells by targeting TRIM25 (tripartite motif containing 25)-mediated GPX4 degradation in pancreatic cells, both in vitro and in various mouse models, such as xenografts, orthotopic models, and transgenic models [36] (Fig