Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface
First, the refinement of diagnostic criteria and advances in imaging technologies have substantially improved disease detectionparticularly through the widespread adoption of the revised Atlanta classification (RAC) in North America, Europe, and the AsiaPacific region, 9,10 as well as the growing use of advanced imaging tools such as magnetic resonance cholangiopancreatography (MRCP) and endoscopic ultrasound (EUS)
These include redness, swelling, tenderness, itching, bruising, and occasionally a small lump or bump under the skin that may persist for several days
Neural precursor cell expressed, developmentally downregulated 9 (NEDD9), a scaffolding protein associated with poor prognosis in multiple cancers, shows significantly elevated expression in hepatocellular carcinoma (HCC) tissues versus adjacent non-tumor liver (84)