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Eat me signals include Phosphatidylserine (PS) exposure (Zhang et al., 2012), changes in cell surface charges and glycosylation patterns (Khalaji et al., 2023), cell adhesion molecule 3(ICAM-3) (Starling et al., 1995
Consequently, the development of kidney-specific antisense oligonucleotide (ASO) or adeno-associated viral (AAV) transduction methods is advantageous, as these approaches can selectively inhibit ANGPTL4 in proximal tubules, glomerular podocytes, and glomerular endothelial cells, thereby avoiding the adverse systemic effects associated with whole-body ANGPTL4 loss (Srivastava et al., 2024)
It is generally understood that new biomarkers discovered after application of bioinformatics analysis of omics datasets should be verified using more focused forms of analysis
Many people find that their tolerance decreases
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