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Using anaerobic incubation and a gnotobiotic mouse model, we confirmed the role of these microbes in TMA/TMAO production

A single dose of exenatide had no effect on blood flow velocity in the middle cerebral artery in elderly healthy volunteers: randomized, placebo-controlled, double-blind clinical trial

Moreover, in the SNI-induced chronic neuropathic pain model, heat hyperalgesia was alleviated in mice challenged with SNI and administered intraperitoneal injections of 50 g of exendin 2029, with effects observed as early as 1 hour postadministration and peaking at 2 hours compared with those in the vehicle-administered group (Supplementary Fig