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Studies have shown that in those with AUD, networks affecting reward and self-control such as the striatum and orbitofrontal cortex have decreased synchronous activity, which is correlated with years of heavy alcohol consumption (6)

In this regard, CB1 activation suppresses M2 macrophage polarization [113]

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A study funded by Eli Lilly and Company, the manufacturer of both Jardiance and Trulicity, found that patients who took both medications had better control of blood glucose levels than patients who took Jardiance alone