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MOTS-c is also contraindicated for people who take AMPK-activating medicines, such as metformin , thiazolidinediones , and aspirin , as well as anyone with an active cancer diagnosis and people who are pregnant or breastfeeding

Tier 1 protocols may range from $300-600 monthly, Tier 2 from $500-1,200 monthly, and Tier 3 from $800-2,000 monthly depending on complexity

The article elaborates on the coverage criteria established by Blue Cross, highlighting the necessity for prior authorization and documentation of medical necessity