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The mice showed pronounced increases in body weight, food intake, and levels of liver injury markers, such as plasma alanine transaminase (ALT), aspartate aminotransferase (AST), tissue inhibitor of metalloproteinase-1 (TIMP-1), triglyceride (TG), cholesterol, and low-density lipoprotein cholesterol (LDL-C), compared to normal mice

RNA isolation and quantitative reverse transcription-polymerase chain reaction Total RNA was isolated using the ISOGEN reagent (Nippon Gene) and reverse transcribed to cDNA using the ReverTra Ace qPCR RT Kit (Toyobo, Osaka, Japan)

With design in place, our development team brought the platform to life, working closely with Fridays team at every step

Could be useful evidence to show GP of symptoms returning before next injection