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doi: 10.1038/ni.1835ni.1835 10 MenziesAMJohnsonDBRamanujamSAtkinsonVGWongANMParkJJet al

Monitoring fasting glucose and considering insulin sensitivity markers during cycles helps identify early signs of metabolic disruption

Elevated circulating inflammatory markers, including C-reactive protein and leukocyte counts, have been consistently reported in PCOS populations, even after adjustment for adiposity [5, 6], suggesting that inflammatory processes may contribute to disease expression rather than merely reflect obesity-related confounding