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A 2001 editorial in the European Journal of Anaesthesiology described DSIP as "incredibly safe," noting that no dose had ever killed an animal subject in research, and the only human side effects observed were transient headache, nausea, and vertigo

Stamenkovic, Mesenchymal stromal cells in cancer?: a review of their immunomodulatory functions and dual effects on tumor progression S Galland and I Stamenkovic, Journal of Pathology., pp

Other silybin derivatives are in development, such as the silybinphosphatidylcholine complex, which has shown some efficacy with treatment of non-fatty liver disease (Ferenci, 2016)

For example, theBC Health Guidelines offer helpful information