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Although the levels of demethylation during the pre-implantation period are significant, a portion of DNA methylation will be kept during the reprogramming after fertilization, including the imprinted genes, which represent an inheritance from the paternal environment to the offspring phenotype (Jiang et al., 2018)

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It binds to the GHRH-R receptor on somatotroph cells of the anterior pituitary and triggers GH release via the cAMP/PKA pathway

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