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Acetaminophen (Tylenol): 5065% of pregnant women use acetaminophen.[67] When CYP1A2 is suppressed, both caffeine and acetaminophen are shunted to the backup enzyme CYP2E1, generating the toxic metabolite NAPQI that depletes glutathione

Within the cell, the structure of organelles is inherently optimized to enhance their functions 53

While necessary, this phase transforms toxins into "reactive intermediate metabolites" that are frequently more toxic and volatile than the original substance, generating massive amounts of free radicals

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