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Previously, Koeth et al

Contrave should NOT be used if you: Have uncontrolled high blood pressure Have a seizure disorder or history of seizures Are taking monoamine oxidase inhibitors (MAOIs) Have an eating disorder (bulimia or anorexia) Are dependent on opioids or going through opioid withdrawal Are taking other medications containing bupropion Contrave can also cause increased blood pressure so regular monitoring is recommended

Thus, because theres no third-party investigator for the plan, corresponding study results may be biased, she explains

The HealthRX.com Co-Prescribing Decision Framework Clinicians evaluating this combination should assess three domains before writing both prescriptions