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Further studies will be needed to investigate the physiological relevance of inhibiting or activating NAPRT in non-cancer chronic conditions, such as aging and age-associated diseases

The question has shifted from "is it too expensive to cover GLP-1?" to "is it too expensive not to?" As clinical data accumulates showing that GLP-1 medications reduce the incidence and severity of the most expensive chronic diseases, payers are recognizing that proactive treatment of obesity saves money compared to treating its downstream consequences

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