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Oxidized low-density lipoprotein associates with cardiovascular disease by a vicious cycle of atherosclerosis and inflammation: A systematic review and meta-analysis

Our previous work using a zebrafish model system revealed that GCGR deficiency not only induces -cell hyperplasia but also upregulates glucagon gene ( Gcg ) expression in cells 16

Conversely, our analysis suggests that use of GLP-1 RAs is unlikely to be cost-effective from a healthcare or societal perspective (based solely on their cardiovascular benefits) in either population at current prices

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