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Estrogen has an antioxidant function, and estrogen deficiency can inhibit the Nrf2/GPX4 pathway to induce ferroptosis (73)

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As a histone deacetylase (HDAC) inhibitor, butyrate acts directly on B-cell intrinsic pathways without relying on GPR signaling or serving as an energy substrate

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doi: 10.1038/s41420-021-00579-w

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CCK8 cell proliferation assays were performed by measuring absorbance at 450 nm by using a microplate reader (Thermo Fisher, USA) after incubation at 37 C for 14 h

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