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Poor sleep disrupts hunger hormones and reduces insulin sensitivity, making further weight loss harder

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Affordability improvements may expand coverage: Frdric Leblanc, a pharmacist at iA Financial, notes that insurers are "preparing for everything we need to do so that everybody benefits from a lower price, both in diabetes and eventually in weight management." Sandoz CEO Richard Saynor has described Canada as the world's second-largest GLP-1 market

Appetite signaling, satiety, and gastrointestinal effects may be noticed earlier, but the outcomes people usually care about in the clinical literature, especially body-weight change, were measured over long study windows rather than days